If your estimated tax liability for the year is ₹10,000 or more, yes — in four instalments: 15% by 15 June, 45% by 15 September, 75% by 15 December, and 100% by 15 March.
Loss-making startups often assume this doesn't concern them, then get caught by profitability arriving mid-year, interest income on idle fundraise money, or capital gains. Shortfalls attract interest under Sections 234B and 234C — not fatal, but pure waste.
The fix is boring and effective: a quarterly tax estimate as part of your management accounts, refreshed before each instalment date. It's a standard part of our Virtual CFO rhythm.